| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DNAJC8 |
| Gene ID: | 22826 |
| Uniprot ID: | DNJC8_HUMAN |
| Immunogen Region: | 1-253 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-253 of human DNAJC8 (NP_055095.2). |
| Immunogen Sequence: | MAASGESGTSGGGGSTEEAF MTFYSEVKQIEKRDSVLTSK NQIERLTRPGSSYFNLNPFE VLQIDPEVTDEEIKKRFRQL SILVHPDKNQDDADRAQKAF EAVDKAYKLLLDQEQKKRAL DVIQAGKEYVEHTVKERKKQ LKKEGKPTIVEEDDPELFKQ AVYKQTMKLFAELEIKRKER EAKEMHERKRQREEEIEAQE KAKREREWQKNFEESRDGRV DSWRNFQANTKGKKEKKNR |
| Tissue Specificity | Ubiquitous. |
| Function | Suppresses polyglutamine (polyQ) aggregation of ATXN3 in neuronal cells. |
| Protein Name | Dnaj Homolog Subfamily C Member 8Splicing Protein Spf31 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dnaj Homolog Subfamily C Member 8 antibodyAnti-Splicing Protein Spf31 antibodyAnti-DNAJC8 antibodyAnti-SPF31 antibodyAnti-HSPC315 antibodyAnti-HSPC331 antibody |
Information sourced from Uniprot.org