• Western blot analysis of extracts of various cell lines, using DNAJC7 antibody (STJ23402) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-DNAJC7 antibody (230-380) (STJ23402)

SKU:
STJ23402

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DNAJC7 (230-380) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DNAJC7
Gene ID: 7266
Uniprot ID: DNJC7_HUMAN
Immunogen Region: 230-380
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 230-380 of human DNAJC7 (NP_003306.3).
Immunogen Sequence: VQFFVQALRMAPDHEKACIA CRNAKALKAKKEDGNKAFKE GNYKLAYELYTEALGIDPNN IKTNAKLYCNRGTVNSKLRK LDDAIEDCTNAVKLDDTYIK AYLRRAQCYMDTEQYEEAVR DYEKVYQTEKTKEHKQLLKN AQLELKKSKRK
Function Acts as co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes. Recruits NR1I3 to the cytoplasm.
Protein Name Dnaj Homolog Subfamily C Member 7
Tetratricopeptide Repeat Protein 2
Tpr Repeat Protein 2
Database Links Reactome: R-HSA-3371453
Cellular Localisation Cytoplasm
Nucleus
Cytoskeleton
Colocalizes With Nr1i3 To Microtubules
Alternative Antibody Names Anti-Dnaj Homolog Subfamily C Member 7 antibody
Anti-Tetratricopeptide Repeat Protein 2 antibody
Anti-Tpr Repeat Protein 2 antibody
Anti-DNAJC7 antibody
Anti-TPR2 antibody
Anti-TTC2 antibody

Information sourced from Uniprot.org

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