• Western blot analysis of extracts of various cell lines, using DHRS3 antibody (STJ116105) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.

Anti-DHRS3 antibody (30-150) (STJ116105)

SKU:
STJ116105

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Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DHRS3 (30-150) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DHRS3
Gene ID: 9249
Uniprot ID: DHRS3_HUMAN
Immunogen Region: 30-150
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-150 of human DHRS3 (NP_004744.2).
Immunogen Sequence: PAKLRDLSRENVLITGGGRG IGRQLAREFAERGARKIVLW GRTEKCLKETTEEIRQMGTE CHYFICDVGNREEVYQTAKA VREKVGDITILVNNAAVVHG KSLMDSDDDALLKSQHINTL G
Tissue Specificity Widely expressed with highest levels found in heart, placenta, lung, liver, kidney, pancreas, thyroid, testis, stomach, trachea and spinal cord. Lower levels found in skeletal muscle, intestine and lymph node. No expression detected in brain. In the retina, expressed in cone but not rod outer segments.
Function Catalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH.
Protein Name Short-Chain Dehydrogenase/Reductase 3
Dd83.1
Retinal Short-Chain Dehydrogenase/Reductase 1
Retsdr1
Retinol Dehydrogenase 17
Short Chain Dehydrogenase/Reductase Family 16c Member 1
Database Links Reactome: R-HSA-2187335
Reactome: R-HSA-5365859
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Short-Chain Dehydrogenase/Reductase 3 antibody
Anti-Dd83.1 antibody
Anti-Retinal Short-Chain Dehydrogenase/Reductase 1 antibody
Anti-Retsdr1 antibody
Anti-Retinol Dehydrogenase 17 antibody
Anti-Short Chain Dehydrogenase/Reductase Family 16c Member 1 antibody
Anti-DHRS3 antibody
Anti-RDH17 antibody
Anti-SDR16C1 antibody
Anti-UNQ2424 antibody
Anti-PRO4983 antibody

Information sourced from Uniprot.org

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