Host: | Rabbit |
Applications: | WB, ELISA |
Reactivity: | Human |
Short Description: | Rabbit polyclonal primary antibody against CYP2A6/7/13. |
Note: | FOR RESEARCH USE ONLY (RUO). |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using a epitope-specific immunogen. |
Storage Instruction: | Store at-20°C, and avoid repeat freeze-thaw cycles. |
Concentration: | 1 mg/ml |
Isotype: | IgG |
Dilution Range: | WB 1:500-1:2000ELISA 1:40000 |
Specificity: | CYP2A6/7/13 polyclonal antibody detects endogenous levels of CYP2A6/7/13 protein. |
Uniprot ID: | CP2AD_HUMAN |
Gene ID: | 1553 |
Gene Symbol: | CYP2A13 |
Immunogen: | Synthesized peptide derived from human CYP2A6/7/13. |
Immunogen Region: | Internal |
Tissue Specificity | Expressed in liver and a number of extrahepatic tissues, including nasal mucosa, lung, trachea, brain, mammary gland, prostate, testis, and uterus, but not in heart, kidney, bone marrow, colon, small intestine, spleen, stomach, thymus, or skeletal muscle. |
Function | Exhibits a coumarin 7-hydroxylase activity. Active in the metabolic activation of hexamethylphosphoramide, N,N-dimethylaniline, 2'-methoxyacetophenone, N-nitrosomethylphenylamine, and the tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Possesses phenacetin O-deethylation activity. |
Database Links | Reactome: R-HSA-211935 |
Cellular Localisation | Endoplasmic Reticulum MembranePeripheral Membrane ProteinMicrosome Membrane |
Protein Name | Cytochrome P450 2a13Cypiia13 |
Alternative Names | Anti-Cytochrome P450 2a13 antibodyAnti-Cypiia13 antibodyAnti-CYP2A13 antibody |
Information sourced from Uniprot.org
6 months standard