| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CPQ (20-200) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CPQ |
| Gene ID: |
10404 |
| Uniprot ID: |
CBPQ_HUMAN |
| Immunogen Region: |
20-200 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human CPQ (NP_057218.1). |
| Immunogen Sequence: |
GKAICKNGISKRTFEEIKEE IASCGDVAKAIINLAVYGKA QNRSYERLALLVDTVGPRLS GSKNLEKAIQIMYQNLQQDG LEKVHLEPVRIPHWERGEES AVMLEPRIHKIAILGLGSSI GTPPEGITAEVLVVTSFDEL QRRASEARGKIVVYNQPYIN YSRTVQYRTQGAVEAAKVGA L |
| Tissue Specificity | Mainly detected in blood plasma. Abundant in placenta and kidney. Present at low level in muscles, liver and skin fibroblasts. Not detected in brain or white blood cells (at protein level). |
| Post Translational Modifications | N-glycosylated. The secreted form is modified by hybrid or complex type oligosaccharide chains. |
| Function | Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes the hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor. |
| Protein Name | Carboxypeptidase QLysosomal DipeptidasePlasma Glutamate Carboxypeptidase |
| Cellular Localisation | Endoplasmic ReticulumGolgi ApparatusLysosomeSecretedSecretion Is Stimulated By Tsh/Thyroid-Stimulating HormoneIns/Insulin And Sst/Somatostatin |
| Alternative Antibody Names | Anti-Carboxypeptidase Q antibodyAnti-Lysosomal Dipeptidase antibodyAnti-Plasma Glutamate Carboxypeptidase antibodyAnti-CPQ antibodyAnti-LCH1 antibodyAnti-PGCP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
