| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CLEC4G |
| Gene ID: |
339390 |
| Uniprot ID: |
CLC4G_HUMAN |
| Immunogen Region: |
54-293 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 54-293 of human CLEC4G (NP_940894.1). |
| Immunogen Sequence: |
SKASTERAALLDGHDLLRTN ASKQTAALGALKEEVGDCHS CCSGTQAQLQTTRAELGEAQ AKLMEQESALRELRERVTQG LAEAGRGREDVRTELFRALE AVRLQNNSCEPCPTSWLSFE GSCYFFSVPKTTWAAAQDHC ADASAHLVIVGGLDEQGFLT RNTRGRGYWLGLRAVRHLGK VQGYQWVDGVSLSFSHWNQG EPNDAWGRENCVMMLHTGLW NDAPCDSEKDGWICEKRHN |
| Tissue Specificity | Expressed exclusively in fetal and adult liver and in lymph nodes. Specifically expressed by endothelial cells lining lymph node and liver sinuses (at protein level). |
| Function | Binds mannose, N-acetylglucosamine (GlcNAc) and fucose, but not galactose, in a Ca(2+)-dependent manner, in vitro. (Microbial infection) Acts as a receptor for Japanese encephalitis virus. (Microbial infection) Acts as a receptor for Ebolavirus. (Microbial infection) Acts as a receptor for SARS-CoV. (Microbial infection) Acts as a receptor for Lassa virus and Lymphocytic choriomeningitis virus glycoprotein. |
| Protein Name | C-Type Lectin Domain Family 4 Member GLiver And Lymph Node Sinusoidal Endothelial Cell C-Type LectinLsectin |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-C-Type Lectin Domain Family 4 Member G antibodyAnti-Liver And Lymph Node Sinusoidal Endothelial Cell C-Type Lectin antibodyAnti-Lsectin antibodyAnti-CLEC4G antibodyAnti-UNQ431 antibodyAnti-PRO792 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and MPG knockout (KO) HeLa cells, using [KO Validated] MPG Rabbit polyclonal antibody (STJ11100043) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89115/357567/STJ11100043_1__91960.1713121694.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and MPG knockout (KO) HeLa cells, using [KO Validated] MPG Rabbit polyclonal antibody (STJ11100043) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.")