• Western blot analysis of lysates from A549 cells, treated with etoposide 25uM 1h, using ITGAV (heavy chain, Cleaved-Lys889) Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Cleaved-Integrin Alpha V HC (K889) Polyclonal Antibody

Anti-Cleaved-ITGAV-K889 antibody (840-889 aa) (STJ90091)

SKU:
STJ90091

Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Cleaved-Integrin alpha-V-K889 (840-889 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ITGAV
Gene ID: 3685
Uniprot ID: ITAV_HUMAN
Immunogen Region: 840-889 aa
Specificity: Cleaved-Integrin Alpha V HC (K889) Polyclonal Antibody detects endogenous levels of fragment of activated Integrin Alpha V HC protein resulting from cleavage adjacent to K889.
Immunogen: The antiserum was produced against synthesized peptide derived from the human ITGAV at the amino acid range 840-889
Protein Name Integrin Alpha-V
Vitronectin Receptor
Vitronectin Receptor Subunit Alpha
Cd Antigen Cd51 Cleaved Into - Integrin Alpha-V Heavy Chain - Integrin Alpha-V Light Chain
Database Links Reactome: R-HSA-1236973
Reactome: R-HSA-1566948
Reactome: R-HSA-210990
Reactome: R-HSA-2129379
Reactome: R-HSA-216083
Reactome: R-HSA-2173789
Reactome: R-HSA-3000157
Reactome: R-HSA-3000170
Reactome: R-HSA-3000178
Reactome: R-HSA-4420097
Reactome: R-HSA-445144
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Focal Adhesion
Alternative Antibody Names Anti-Integrin Alpha-V antibody
Anti-Vitronectin Receptor antibody
Anti-Vitronectin Receptor Subunit Alpha antibody
Anti-Cd Antigen Cd51 Cleaved Into - Integrin Alpha-V Heavy Chain - Integrin Alpha-V Light Chain antibody
Anti-ITGAV antibody
Anti-MSK8 antibody
Anti-VNRA antibody
Anti-VTNR antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance