| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CHST5 (232-411) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CHST5 |
| Gene ID: |
23563 |
| Uniprot ID: |
CHST5_HUMAN |
| Immunogen Region: |
232-411 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 232-411 of human CHST5 (NP_078809.2). |
| Immunogen Sequence: |
SREAAGPILARDNGIVLGTN GKWVEADPHLRLIREVCRSH VRIAEAATLKPPPFLRGRYR LVRFEDLAREPLAEIRALYA FTGLTLTPQLEAWIHNITHG SGIGKPIEAFHTSSRNARNV SQAWRHALPFTKILRVQEVC AGALQLLGYRPVYSADQQRD LTLDLVLPRGPDHFSWASPD |
| Tissue Specificity | Predominantly expressed in small and large intestines and colon. Weakly expressed in lymphocytes. Not expressed in other tissues. Down-regulated in colonic adenocarcinomas. |
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues and O-linked sugars of mucin-type acceptors. Acts on the non-reducing terminal GlcNAc of short carbohydrate substrates. However, it does not transfer sulfate to longer carbohydrate substrates that have poly-N-acetyllactosamine structures. Has no activity toward keratan. Not involved in generating HEV-expressed ligands for SELL. Its substrate specificity may be influenced by its subcellular location. |
| Protein Name | Carbohydrate Sulfotransferase 5Galactose/N-Acetylglucosamine/N-Acetylglucosamine 6-O-Sulfotransferase 4-AlphaGst4-AlphaIntestinal N-Acetylglucosamine-6-O-SulfotransferaseI-Glcnac6stIntestinal Glcnac-6-SulfotransferaseHign6stN-Acetylglucosamine 6-O-Sulfotransferase 3Glcnac6st-3Gn6st-3 |
| Database Links | Reactome: R-HSA-2022854 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinGolgi MembraneEarly Secretory Pathway |
| Alternative Antibody Names | Anti-Carbohydrate Sulfotransferase 5 antibodyAnti-Galactose/N-Acetylglucosamine/N-Acetylglucosamine 6-O-Sulfotransferase 4-Alpha antibodyAnti-Gst4-Alpha antibodyAnti-Intestinal N-Acetylglucosamine-6-O-Sulfotransferase antibodyAnti-I-Glcnac6st antibodyAnti-Intestinal Glcnac-6-Sulfotransferase antibodyAnti-Hign6st antibodyAnti-N-Acetylglucosamine 6-O-Sulfotransferase 3 antibodyAnti-Glcnac6st-3 antibodyAnti-Gn6st-3 antibodyAnti-CHST5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
