| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NOG (28-232) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NOG |
| Gene ID: |
9241 |
| Uniprot ID: |
NOGG_HUMAN |
| Immunogen Region: |
28-232 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 28-232 of human NOG (NP_005441.1). |
| Immunogen Sequence: |
QHYLHIRPAPSDNLPLVDLI EHPDPIFDPKEKDLNETLLR SLLGGHYDPGFMATSPPEDR PGGGGGAAGGAEDLAELDQL LRQRPSGAMPSEIKGLEFSE GLAQGKKQRLSKKLRRKLQM WLWSQTFCPVLYAWNDLGSR FWPRYVKVGSCFSKRSCSVP EGMVCKPSKSVHLTVLRWRC QRRGGQRCGWIPIQYPIISE CKCSC |
| Function | Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. Essential for cartilage morphogenesis and joint formation. Inhibits chondrocyte differentiation through its interaction with GDF5 and, probably, GDF6. |
| Protein Name | Noggin |
| Database Links | Reactome: R-HSA-201451Reactome: R-HSA-9793380 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Noggin antibodyAnti-NOG antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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