| Tissue Specificity | Widely expressed. Expressed a high level in spinal chord, heart, spleen, thyroid, pituitary gland, adrenal gland, peripheral blood leukocytes, thymus, lung, small intestine, fetal kidney, fetal spleen and fetal lung. |
| Function | Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Activity toward partially desulfated dermatan sulfate is however lower. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor. |
| Protein Name | Carbohydrate Sulfotransferase 12Chondroitin 4-O-Sulfotransferase 2Chondroitin 4-Sulfotransferase 2C4st-2C4st2Sulfotransferase Hlo |
| Database Links | Reactome: R-HSA-2022870 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Carbohydrate Sulfotransferase 12 antibodyAnti-Chondroitin 4-O-Sulfotransferase 2 antibodyAnti-Chondroitin 4-Sulfotransferase 2 antibodyAnti-C4st-2 antibodyAnti-C4st2 antibodyAnti-Sulfotransferase Hlo antibodyAnti-CHST12 antibodyAnti-UNQ500 antibodyAnti-PRO1017 antibody |
Information sourced from Uniprot.org
