| Tissue Specificity | Widely expressed. |
| Function | DNA-dependent ATPase that plays a role in chromatin remodeling. Regulates transcription by disrupting nucleosomes in a largely non-sliding manner which strongly increases the accessibility of chromatin. Activates transcription of specific genes in response to oxidative stress through interaction with NFE2L2. (Microbial infection) Acts as a transcriptional repressor of different viruses including influenza virus or papillomavirus. During influenza virus infection, the viral polymerase complex localizes CHD6 to inactive chromatin where it gets degraded in a proteasome independent-manner. |
| Protein Name | Chromodomain-Helicase-Dna-Binding Protein 6Chd-6Atp-Dependent Helicase Chd6Radiation-Induced Gene B Protein |
| Cellular Localisation | NucleusNucleoplasmEnriched At Sites Of Mrna SynthesisDuring Influenza A Virus InfectionLocalizes To Inactive Chromatin |
| Alternative Antibody Names | Anti-Chromodomain-Helicase-Dna-Binding Protein 6 antibodyAnti-Chd-6 antibodyAnti-Atp-Dependent Helicase Chd6 antibodyAnti-Radiation-Induced Gene B Protein antibodyAnti-CHD6 antibodyAnti-CHD5 antibodyAnti-KIAA1335 antibodyAnti-RIGB antibody |
Information sourced from Uniprot.org
