| Host: |
Rabbit |
| Applications: |
IHC |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-Carcinoembryonic antigen-Related Cell Adhesion Molecule 8 (35-319) is suitable for use in Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S4943RM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
IHC-P 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CEACAM8 |
| Gene ID: |
1088 |
| Uniprot ID: |
CEAM8_HUMAN |
| Immunogen Region: |
35-319 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 35-319 of human CD66b/CEACAM8. |
| Immunogen Sequence: |
QLTIEAVPSNAAEGKEVLLL VHNLPQDPRGYNWYKGETVD ANRRIIGYVISNQQITPGPA YSNRETIYPNASLLMRNVTR NDTGSYTLQVIKLNLMSEEV TGQFSVHPETPKPSISSNNS NPVEDKDAVAFTCEPETQNT TYLWWVNGQSLPVSPRLQLS NGNRTLTLLSVTRNDVGPYE CEIQNPASANFSDPVTLNVL YGPDAPTISPSDTYYHAGVN LNLSCHAASNPPSQYSWSV |
| Tissue Specificity | Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow. |
| Post Translational Modifications | Glycosylated. |
| Function | Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Heterophilic interaction with CEACAM8 occurs in activated neutrophils. |
| Protein Name | Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8Cd67 AntigenCarcinoembryonic Antigen Cgm6Non-Specific Cross-Reacting Antigen Nca-95Cd Antigen Cd66b |
| Database Links | Reactome: R-HSA-1566977Reactome: R-HSA-202733Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorCell Surface |
| Alternative Antibody Names | Anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 antibodyAnti-Cd67 Antigen antibodyAnti-Carcinoembryonic Antigen Cgm6 antibodyAnti-Non-Specific Cross-Reacting Antigen Nca-95 antibodyAnti-Cd Antigen Cd66b antibodyAnti-CEACAM8 antibodyAnti-CGM6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
