• Western blot analysis of extracts of HepG2 cells, using CDS2 antibody (STJ26590). Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.

Anti-CDS2 antibody (1-100) (STJ26590)

SKU:
STJ26590

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CDS2 (1-100) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CDS2
Gene ID: 8760
Uniprot ID: CDS2_HUMAN
Immunogen Region: 1-100
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CDS2 (NP_003809.1).
Immunogen Sequence: MTELRQRVAHEPVAPPEDKE SESEAKVDGETASDSESRAE SAPLPVSADDTPEVLNRALS NLSSRWKNWWVRGILTLAMI AFFFIIIYLGPMVLMIIVMC
Tissue Specificity Widely expressed. Expressed in heart, brain and retina, and to a lesser extent in placenta, lung, liver, skeletal muscle, kidney and pancreas.
Function Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol. Exhibits specificity for the nature of the acyl chains at the sn-1 and sn-2 positions in the substrate, PA and the preferred acyl chain composition is 1-stearoyl-2-arachidonoyl-sn-phosphatidic acid. Plays an important role in regulating the growth and maturation of lipid droplets which are storage organelles at the center of lipid and energy homeostasis.
Protein Name Phosphatidate Cytidylyltransferase 2
Cdp-Dag Synthase 2
Cdp-Dg Synthase 2
Cdp-Diacylglycerol Synthase 2
Cds 2
Cdp-Diglyceride Pyrophosphorylase 2
Cdp-Diglyceride Synthase 2
Ctp -Phosphatidate Cytidylyltransferase 2
Database Links Reactome: R-HSA-1483148
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Phosphatidate Cytidylyltransferase 2 antibody
Anti-Cdp-Dag Synthase 2 antibody
Anti-Cdp-Dg Synthase 2 antibody
Anti-Cdp-Diacylglycerol Synthase 2 antibody
Anti-Cds 2 antibody
Anti-Cdp-Diglyceride Pyrophosphorylase 2 antibody
Anti-Cdp-Diglyceride Synthase 2 antibody
Anti-Ctp -Phosphatidate Cytidylyltransferase 2 antibody
Anti-CDS2 antibody

Information sourced from Uniprot.org

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