| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CDS2 (1-100) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CDS2 |
| Gene ID: |
8760 |
| Uniprot ID: |
CDS2_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CDS2 (NP_003809.1). |
| Immunogen Sequence: |
MTELRQRVAHEPVAPPEDKE SESEAKVDGETASDSESRAE SAPLPVSADDTPEVLNRALS NLSSRWKNWWVRGILTLAMI AFFFIIIYLGPMVLMIIVMC |
| Tissue Specificity | Widely expressed. Expressed in heart, brain and retina, and to a lesser extent in placenta, lung, liver, skeletal muscle, kidney and pancreas. |
| Function | Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol. Exhibits specificity for the nature of the acyl chains at the sn-1 and sn-2 positions in the substrate, PA and the preferred acyl chain composition is 1-stearoyl-2-arachidonoyl-sn-phosphatidic acid. Plays an important role in regulating the growth and maturation of lipid droplets which are storage organelles at the center of lipid and energy homeostasis. |
| Protein Name | Phosphatidate Cytidylyltransferase 2Cdp-Dag Synthase 2Cdp-Dg Synthase 2Cdp-Diacylglycerol Synthase 2Cds 2Cdp-Diglyceride Pyrophosphorylase 2Cdp-Diglyceride Synthase 2Ctp -Phosphatidate Cytidylyltransferase 2 |
| Database Links | Reactome: R-HSA-1483148 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Phosphatidate Cytidylyltransferase 2 antibodyAnti-Cdp-Dag Synthase 2 antibodyAnti-Cdp-Dg Synthase 2 antibodyAnti-Cdp-Diacylglycerol Synthase 2 antibodyAnti-Cds 2 antibodyAnti-Cdp-Diglyceride Pyrophosphorylase 2 antibodyAnti-Cdp-Diglyceride Synthase 2 antibodyAnti-Ctp -Phosphatidate Cytidylyltransferase 2 antibodyAnti-CDS2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
