| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CDKAL1 (1-230) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:10-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CDKAL1 |
| Gene ID: |
54901 |
| Uniprot ID: |
CDKAL_HUMAN |
| Immunogen Region: |
1-230 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human CDKAL1 (NP_060244.2). |
| Immunogen Sequence: |
MPSASCDTLLDDIEDIVSQE DSKPQDRHFVRKDVVPKVRR RNTQKYLQEEENSPPSDSTI PGIQKIWIRTWGCSHNNSDG EYMAGQLAAYGYKITENASD ADLWLLNSCTVKNPAEDHFR NSIKKAQEENKKIVLAGCVP QAQPRQDYLKGLSIIGVQQI DRVVEVVEETIKGHSVRLLG QKKDNGRRLGGARLDLPKIR KNPLIEIISINTGCLNACTY CKTKHARGNL |
| Tissue Specificity | Expressed in pancreatic islets. |
| Function | Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine. |
| Protein Name | Threonylcarbamoyladenosine Trna MethylthiotransferaseCdk5 Regulatory Subunit-Associated Protein 1-Like 1Trna-T(6a37 Methylthiotransferase |
| Database Links | Reactome: R-HSA-6782315 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinIs A Tail-Anchored Protein That Exploits The Tcr40 Pathway For Insertion Into The Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-Threonylcarbamoyladenosine Trna Methylthiotransferase antibodyAnti-Cdk5 Regulatory Subunit-Associated Protein 1-Like 1 antibodyAnti-Trna-T(6a37 Methylthiotransferase antibodyAnti-CDKAL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
