| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CDC7 (275-574) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CDC7 |
| Gene ID: |
8317 |
| Uniprot ID: |
CDC7_HUMAN |
| Immunogen Region: |
275-574 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 275-574 of human CDC7 (NP_001127892.1). |
| Immunogen Sequence: |
EGSVGLSVQRSVFGERNFNI HSSISHESPAVKLMKQSKTV DVLSRKLATKKKAISTKVMN SAVMRKTASSCPASLTCDCY ATDKVCSICLSRRQQVAPRA GTPGFRAPEVLTKCPNQTTA IDMWSAGVIFLSLLSGRYPF YKASDDLTALAQIMTIRGSR ETIQAAKTFGKSILCSKEVP AQDLRKLCERLRGMDSSTPK LTSDIQGHASHQPAISEKTD HKASCLVQTPPGQYSGNSF |
| Function | Kinase involved in initiation of DNA replication. Phosphorylates critical substrates that regulate the G1/S phase transition and initiation of DNA replication, such as MCM proteins and CLASPIN. |
| Protein Name | Cell Division Cycle 7-Related Protein KinaseCdc7-Related KinaseHscdc7Hucdc7 |
| Database Links | Reactome: R-HSA-176187Reactome: R-HSA-68962Reactome: R-HSA-8953750 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Cell Division Cycle 7-Related Protein Kinase antibodyAnti-Cdc7-Related Kinase antibodyAnti-Hscdc7 antibodyAnti-Hucdc7 antibodyAnti-CDC7 antibodyAnti-CDC7L1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
