Anti-CD337/NKp30 Neutralizing nanobody [VHH1] (STJN000630)

SKU:
STJN000630
£378.50 - £1,632.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Alpaca
Applications: ELISA/Neut
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Alpaca monoclonal nanobody anti-Natural Cytotoxicity Triggering Receptor 3 is suitable for use in ELISA and Universal research applications.
Clonality : Monoclonal
Clone ID : VHH1
Conjugation: Unconjugated
Isotype: VHH-8His-Cys-tag
Formulation: 0.01M PBS, pH 7.4.
Purification: Protein A/G purified from cell culture supernatant.
Concentration: 1 mg/mL
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.
Gene Symbol: NCR3
Gene ID: 259197
Uniprot ID: NCTR3_HUMAN
Function Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation.
Protein Name Natural Cytotoxicity Triggering Receptor 3
Activating Natural Killer Receptor P30
Natural Killer Cell P30-Related Protein
Nk-P30
Nkp30
Cd Antigen Cd337
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Nanobody Names Anti-Natural Cytotoxicity Triggering Receptor 3 nanobody
Anti-Activating Natural Killer Receptor P30 nanobody
Anti-Natural Killer Cell P30-Related Protein nanobody
Anti-Nk-P30 nanobody
Anti-Nkp30 nanobody
Anti-Cd Antigen Cd337 nanobody
Anti-NCR3 nanobody
Anti-1C7 nanobody
Anti-LY117 nanobody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJN000629 Anti-CD337/NKp30 nanobody [VHH2] (STJN000629) Alpaca Monoclonal Human ELISA
STJN000623 Anti-CASP3 nanobody [VHH1] (STJN000623) Alpaca Monoclonal Human ELISA
STJP011719 Human CD337/NKp30 protein (Recombinant-Active) (C-His) (STJP011719) Mammalian Cells
STJP002593 Human NCR3/NKp30/CD337 protein (Recombinant) (C-hFc & His) (STJP002593) HEK293 cells
STJP001661 Human NKp30/NCR3/CD337 protein (Recombinant) (C-His-Avi) {Biotin} (STJP001661) HEK293

Related Products

!