Anti-CD21 antibody [2G9] (STJ16101703)

Anti-CD21 antibody [2G9] (STJ16101703)

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STJ16101703-1
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Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-CD21 is suitable for use in Immunohistochemistry research applications.
Clonality : Monoclonal
Clone ID : 2G9
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: Tissue culture supernatant with sodium azide
Concentration: >=326 mg/L
Dilution Range: IHC-P 1:80
Storage Instruction: Store at 2-8°C upon receipt.
Immunogen: Prokaryotic recombinant protein corresponding to the external domain of the human CD21 molecule.
Background CD21 antigen is a type I integral membrane glycoprotein of molecular weight 140 kD, which functions as the receptor for the C3d fragment of the third complement component. The CD21 molecule, present on mature B cells, is involved in transmitting growth-promoting signals to the interior of the B cell and acts as a receptor for Epstein-Barr virus. CD21 antigen is reported to be found in B cell chronic lymphocytic leukemias and in a subset of T cell acute lymphocytic leukemias but is absent on T lymphocytes, monocytes and granulocytes. CD21 antigen is also reported to be expressed in follicular dendritic cells and in follicular and mantle cell lymphomas, mature leukemias and lymphomas.

Information sourced from Uniprot.org

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