Anti-CD13 antibody [38C12] (STJ16101697)

Anti-CD13 antibody [38C12] (STJ16101697)

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STJ16101697-1
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Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-CD13 is suitable for use in Immunohistochemistry research applications.
Clonality : Monoclonal
Clone ID : 38C12
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Tissue culture supernatant with sodium azide
Concentration: >=19 mg/L
Dilution Range: IHC-P 1:80
Storage Instruction: Store at 2-8°C upon receipt.
Immunogen: Recombinant prokaryotic fusion protein corresponding to the C-terminal region of the extracellular domain.
Background CD13 antigen, also known as aminopeptidase N, is a member of type II integral membrane metalloproteases, which also includes the leukocyte antigens CD10, CD26, CD73 and BP-1. CD13 antigen is a receptor for the coronaviruses which cause respiratory disease in humans and several animal species. The antigen functions as a zinc-binding metalloprotease which plays a role in cell surface antigen presentation by trimming the N-terminal amino acids from MHC class II-bound peptides. CD13 antigen is reported to be expressed on granulocytes, monocytes and their precursors, most acute myeloid leukemias and a smaller proportion of acute lymphoid leukemias. Non-hematopoietic cells which express CD13 antigen include epithelial cells, renal proximal tubules, intestinal brush border, endothelial cells, fibroblasts, brain cells, bone marrow, osteoclasts and cells lining the bile canaliculi.

Information sourced from Uniprot.org

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