• Anti-CD13/ANPEP antibody [B-F10] {AF488} (STJA0002676)

Anti-CD13/ANPEP antibody [B-F10] {AF488} (STJA0002676)

SKU:
STJA0002676

£159.50 - £363.50
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Host: Mouse
Applications: FC
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Aminopeptidase N is suitable for use in Flow Cytometry research applications.
Clonality: Monoclonal
Clone ID: B-F10
Conjugation: AF488
Isotype: IgG1k
Formulation: PBS with 0.05% Proclin300, 1% BSA
Storage Instruction: Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.
Gene Symbol: ANPEP
Gene ID: 290
Uniprot ID: AMPN_HUMAN
Tissue Specificity Expressed in epithelial cells of the kidney, intestine, and respiratory tract.granulocytes, monocytes, fibroblasts, endothelial cells, cerebral pericytes at the blood-brain barrier, synaptic membranes of cells in the CNS. Also expressed in endometrial stromal cells, but not in the endometrial glandular cells. Found in the vasculature of tissues that undergo angiogenesis and in malignant gliomas and lymph node metastases from multiple tumor types but not in blood vessels of normal tissues. A soluble form has been found in plasma. It is found to be elevated in plasma and effusions of cancer patients.
Post Translational Modifications Sulfated. N- and O-glycosylated. May undergo proteolysis and give rise to a soluble form.
Function Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity. (Microbial infection) Acts as a receptor for human coronavirus 229E/HCoV-229E. In case of human coronavirus 229E (HCoV-229E) infection, serves as receptor for HCoV-229E spike glycoprotein. (Microbial infection) Mediates as well Human cytomegalovirus (HCMV) infection.
Protein Name Aminopeptidase N
Ap-N
Hapn
Alanyl Aminopeptidase
Aminopeptidase M
Ap-M
Microsomal Aminopeptidase
Myeloid Plasma Membrane Glycoprotein Cd13
Gp150
Cd Antigen Cd13
Database Links Reactome: R-HSA-2022377
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Also Found As A Soluble Form
Alternative Antibody Names Anti-Aminopeptidase N antibody
Anti-Ap-N antibody
Anti-Hapn antibody
Anti-Alanyl Aminopeptidase antibody
Anti-Aminopeptidase M antibody
Anti-Ap-M antibody
Anti-Microsomal Aminopeptidase antibody
Anti-Myeloid Plasma Membrane Glycoprotein Cd13 antibody
Anti-Gp150 antibody
Anti-Cd Antigen Cd13 antibody
Anti-ANPEP antibody
Anti-APN antibody
Anti-CD13 antibody
Anti-PEPN antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance