• Western blot analysis of various lysates, using CD112 Rabbit polyclonal antibody (STJ11105181) at 1:2000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-CD112 antibody (STJ11105181)

SKU:
STJ11105181

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CD112 is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: Nectin2
Gene ID: 19294
Uniprot ID: NECT2_MOUSE
Immunogen: Recombinant protein of mouse CD112.
Tissue Specificity Brain, spinal cord, spleen, kidney, heart and liver.
Function Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. Probable cell adhesion protein.
Protein Name Nectin-2
Herpes Virus Entry Mediator B
Herpesvirus Entry Mediator B
Hveb
Murine Herpes Virus Entry Protein B
Mhveb
Nectin Cell Adhesion Molecule 2
Poliovirus Receptor Homolog
Poliovirus Receptor-Related Protein 2
Cd Antigen Cd112
Database Links Reactome: R-MMU-198933
Reactome: -MMU-418990
Reactome: -MMU-420597
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Nectin-2 antibody
Anti-Herpes Virus Entry Mediator B antibody
Anti-Herpesvirus Entry Mediator B antibody
Anti-Hveb antibody
Anti-Murine Herpes Virus Entry Protein B antibody
Anti-Mhveb antibody
Anti-Nectin Cell Adhesion Molecule 2 antibody
Anti-Poliovirus Receptor Homolog antibody
Anti-Poliovirus Receptor-Related Protein 2 antibody
Anti-Cd Antigen Cd112 antibody
Anti-Nectin2 antibody
Anti-Mph antibody
Anti-Pvr antibody
Anti-Pvrl2 antibody
Anti-Pvs antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance