Post Translational Modifications | The N-terminal is proteolytically cleaved by proteases associated with inflammatory responses. The processed forms CCL15(22-92), CCL15(25-92) and CCL15(29-92) exhibit increase in CCR1-mediated signaling and chemotaxis assays in vitro. |
Function | Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the CCL15. |
Protein Name | C-C Motif Chemokine 15Chemokine Cc-2Hcc-2Leukotactin-1Lkn-1Mip-1 DeltaMacrophage Inflammatory Protein 5Mip-5Mrp-2bNcc-3Small-Inducible Cytokine A15 Cleaved Into - Ccl15(22-92 - Ccl15(25-92 - Ccl15(29-92 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-C-C Motif Chemokine 15 antibodyAnti-Chemokine Cc-2 antibodyAnti-Hcc-2 antibodyAnti-Leukotactin-1 antibodyAnti-Lkn-1 antibodyAnti-Mip-1 Delta antibodyAnti-Macrophage Inflammatory Protein 5 antibodyAnti-Mip-5 antibodyAnti-Mrp-2b antibodyAnti-Ncc-3 antibodyAnti-Small-Inducible Cytokine A15 Cleaved Into - Ccl15(22-92 - Ccl15(25-92 - Ccl15(29-92 antibodyAnti-CCL15 antibodyAnti-MIP5 antibodyAnti-NCC3 antibodyAnti-SCYA15 antibody |
Information sourced from Uniprot.org