• Western blot analysis of extracts of various cell lines, using CACNG2 Antibody (STJ28620) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-CACNG2 antibody (204-323) (STJ28620)

SKU:
STJ28620

£112.50 - £522.50
Shipping:
Free Shipping
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CACNG2 (204-323) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CACNG2
Gene ID: 10369
Uniprot ID: CCG2_HUMAN
Immunogen Region: 204-323
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 204-323 of human CACNG2 (NP_006069.1).
Immunogen Sequence: RHKQLRATARATDYLQASAI TRIPSYRYRYQRRSRSSSRS TEPSHSRDASPVGIKGFNTL PSTEISMYTLSRDPLKAATT PTATYNSDRDNSFLQVHNCI QKENKDSLHSNTANRRTTPV
Tissue Specificity Brain.
Post Translational Modifications Phosphorylation of Thr-321 impairs interaction with DLG1 and DLG4.
Function Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.
Protein Name Voltage-Dependent Calcium Channel Gamma-2 Subunit
Neuronal Voltage-Gated Calcium Channel Gamma-2 Subunit
Transmembrane Ampar Regulatory Protein Gamma-2
Tarp Gamma-2
Database Links Reactome: R-HSA-112308
Reactome: R-HSA-399719
Reactome: R-HSA-5682910
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Synapse
Synaptosome
Alternative Antibody Names Anti-Voltage-Dependent Calcium Channel Gamma-2 Subunit antibody
Anti-Neuronal Voltage-Gated Calcium Channel Gamma-2 Subunit antibody
Anti-Transmembrane Ampar Regulatory Protein Gamma-2 antibody
Anti-Tarp Gamma-2 antibody
Anti-CACNG2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance