| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CACNG2 (204-323) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CACNG2 |
| Gene ID: |
10369 |
| Uniprot ID: |
CCG2_HUMAN |
| Immunogen Region: |
204-323 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 204-323 of human CACNG2 (NP_006069.1). |
| Immunogen Sequence: |
RHKQLRATARATDYLQASAI TRIPSYRYRYQRRSRSSSRS TEPSHSRDASPVGIKGFNTL PSTEISMYTLSRDPLKAATT PTATYNSDRDNSFLQVHNCI QKENKDSLHSNTANRRTTPV |
| Tissue Specificity | Brain. |
| Post Translational Modifications | Phosphorylation of Thr-321 impairs interaction with DLG1 and DLG4. |
| Function | Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state. |
| Protein Name | Voltage-Dependent Calcium Channel Gamma-2 SubunitNeuronal Voltage-Gated Calcium Channel Gamma-2 SubunitTransmembrane Ampar Regulatory Protein Gamma-2Tarp Gamma-2 |
| Database Links | Reactome: R-HSA-112308Reactome: R-HSA-399719Reactome: R-HSA-5682910 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinSynapseSynaptosome |
| Alternative Antibody Names | Anti-Voltage-Dependent Calcium Channel Gamma-2 Subunit antibodyAnti-Neuronal Voltage-Gated Calcium Channel Gamma-2 Subunit antibodyAnti-Transmembrane Ampar Regulatory Protein Gamma-2 antibodyAnti-Tarp Gamma-2 antibodyAnti-CACNG2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
