| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-C1GALT1 (194-363) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
C1GALT1 |
| Gene ID: |
56913 |
| Uniprot ID: |
C1GLT_HUMAN |
| Immunogen Region: |
194-363 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 194-363 of human C1GALT1 (NP_064541.1). |
| Immunogen Sequence: |
FGRRFKPYVKQGYMSGGAGY VLSKEALKRFVDAFKTDKCT HSSSIEDLALGRCMEIMNVE AGDSRDTIGKETFHPFVPEH HLIKGYLPRTFWYWNYNYYP PVEGPGCCSDLAVSFHYVDS TTMYELEYLVYHLRPYGYLY RYQPTLPERILKEISQANKN EDTKVKLGNP |
| Tissue Specificity | Widely expressed. Highly expressed in kidney, heart, placenta and liver. |
| Function | Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development. |
| Protein Name | Glycoprotein-N-Acetylgalactosamine 3-Beta-Galactosyltransferase 1B3gal-T8Core 1 O-Glycan T-SynthaseCore 1 Udp-Galactose -N-Acetylgalactosamine-Alpha-R Beta 1 -3-Galactosyltransferase 1Beta-1 -3-GalactosyltransferaseCore 1 Beta1 -3-Galactosyltransferase 1C1galt1Core 1 Beta3-Gal-T1 |
| Database Links | Reactome: R-HSA-5083632Reactome: R-HSA-913709 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Glycoprotein-N-Acetylgalactosamine 3-Beta-Galactosyltransferase 1 antibodyAnti-B3gal-T8 antibodyAnti-Core 1 O-Glycan T-Synthase antibodyAnti-Core 1 Udp-Galactose -N-Acetylgalactosamine-Alpha-R Beta 1 -3-Galactosyltransferase 1 antibodyAnti-Beta-1 -3-Galactosyltransferase antibodyAnti-Core 1 Beta1 -3-Galactosyltransferase 1 antibodyAnti-C1galt1 antibodyAnti-Core 1 Beta3-Gal-T1 antibodyAnti-C1GALT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and Adenosine Deaminase (Adenosine Deaminase (ADA) ) knockout (KO) HeLa cells, using [KO Validated] Adenosine Deaminase (ADA) Rabbit polyclonal antibody (STJ11100002) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89075/357532/STJ11100002_1__24167.1713121647.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and Adenosine Deaminase (Adenosine Deaminase (ADA) ) knockout (KO) HeLa cells, using [KO Validated] Adenosine Deaminase (ADA) Rabbit polyclonal antibody (STJ11100002) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.")
