• Western blot analysis of lysates from mouse kidney, using C1GALT1 Rabbit polyclonal antibody (STJ114731) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-C1GALT1 antibody (194-363) (STJ114731)

SKU:
STJ114731

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-C1GALT1 (194-363) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: C1GALT1
Gene ID: 56913
Uniprot ID: C1GLT_HUMAN
Immunogen Region: 194-363
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 194-363 of human C1GALT1 (NP_064541.1).
Immunogen Sequence: FGRRFKPYVKQGYMSGGAGY VLSKEALKRFVDAFKTDKCT HSSSIEDLALGRCMEIMNVE AGDSRDTIGKETFHPFVPEH HLIKGYLPRTFWYWNYNYYP PVEGPGCCSDLAVSFHYVDS TTMYELEYLVYHLRPYGYLY RYQPTLPERILKEISQANKN EDTKVKLGNP
Tissue Specificity Widely expressed. Highly expressed in kidney, heart, placenta and liver.
Function Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development.
Protein Name Glycoprotein-N-Acetylgalactosamine 3-Beta-Galactosyltransferase 1
B3gal-T8
Core 1 O-Glycan T-Synthase
Core 1 Udp-Galactose -N-Acetylgalactosamine-Alpha-R Beta 1 -3-Galactosyltransferase 1
Beta-1 -3-Galactosyltransferase
Core 1 Beta1 -3-Galactosyltransferase 1
C1galt1
Core 1 Beta3-Gal-T1
Database Links Reactome: R-HSA-5083632
Reactome: R-HSA-913709
Cellular Localisation Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-Glycoprotein-N-Acetylgalactosamine 3-Beta-Galactosyltransferase 1 antibody
Anti-B3gal-T8 antibody
Anti-Core 1 O-Glycan T-Synthase antibody
Anti-Core 1 Udp-Galactose -N-Acetylgalactosamine-Alpha-R Beta 1 -3-Galactosyltransferase 1 antibody
Anti-Beta-1 -3-Galactosyltransferase antibody
Anti-Core 1 Beta1 -3-Galactosyltransferase 1 antibody
Anti-C1galt1 antibody
Anti-Core 1 Beta3-Gal-T1 antibody
Anti-C1GALT1 antibody

Information sourced from Uniprot.org