Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-C1GALT1 (194-363) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | C1GALT1 |
Gene ID: | 56913 |
Uniprot ID: | C1GLT_HUMAN |
Immunogen Region: | 194-363 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 194-363 of human C1GALT1 (NP_064541.1). |
Immunogen Sequence: | FGRRFKPYVKQGYMSGGAGY VLSKEALKRFVDAFKTDKCT HSSSIEDLALGRCMEIMNVE AGDSRDTIGKETFHPFVPEH HLIKGYLPRTFWYWNYNYYP PVEGPGCCSDLAVSFHYVDS TTMYELEYLVYHLRPYGYLY RYQPTLPERILKEISQANKN EDTKVKLGNP |
Tissue Specificity | Widely expressed. Highly expressed in kidney, heart, placenta and liver. |
Function | Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development. |
Protein Name | Glycoprotein-N-Acetylgalactosamine 3-Beta-Galactosyltransferase 1 B3gal-T8 Core 1 O-Glycan T-Synthase Core 1 Udp-Galactose -N-Acetylgalactosamine-Alpha-R Beta 1 -3-Galactosyltransferase 1 Beta-1 -3-Galactosyltransferase Core 1 Beta1 -3-Galactosyltransferase 1 C1galt1 Core 1 Beta3-Gal-T1 |
Database Links | Reactome: R-HSA-5083632 Reactome: R-HSA-913709 |
Cellular Localisation | Membrane Single-Pass Type Ii Membrane Protein |
Alternative Antibody Names | Anti-Glycoprotein-N-Acetylgalactosamine 3-Beta-Galactosyltransferase 1 antibody Anti-B3gal-T8 antibody Anti-Core 1 O-Glycan T-Synthase antibody Anti-Core 1 Udp-Galactose -N-Acetylgalactosamine-Alpha-R Beta 1 -3-Galactosyltransferase 1 antibody Anti-Beta-1 -3-Galactosyltransferase antibody Anti-Core 1 Beta1 -3-Galactosyltransferase 1 antibody Anti-C1galt1 antibody Anti-Core 1 Beta3-Gal-T1 antibody Anti-C1GALT1 antibody |
Information sourced from Uniprot.org