| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-C19orf40 (1-215) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FAAP24 |
| Gene ID: |
91442 |
| Uniprot ID: |
FAP24_HUMAN |
| Immunogen Region: |
1-215 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human C19orf40 (NP_689479.1). |
| Immunogen Sequence: |
MEKNPPDDTGPVHVPLGHIV ANEKWRGSQLAQEMQGKIKL IFEDGLTPDFYLSNRCCILY VTEADLVAGNGYRKRLVRVR NSNNLKGIVVVEKTRMSEQY FPALQKFTVLDLGMVLLPVA SQMEASCLVIQLVQEQTKEP SKNPLLGKKRALLLSEPSLL RTVQQIPGVGKVKAPLLLQK FPSIQQLSNASIGELEQVVG QAVAQQIHAFFTQPR |
| Function | Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA. |
| Protein Name | Fanconi Anemia Core Complex-Associated Protein 24Fanconi Anemia-Associated Protein Of 24 Kda |
| Database Links | Reactome: R-HSA-6783310 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Fanconi Anemia Core Complex-Associated Protein 24 antibodyAnti-Fanconi Anemia-Associated Protein Of 24 Kda antibodyAnti-FAAP24 antibodyAnti-C19orf40 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
