| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-C12orf10 (48-376) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MYG1 |
| Gene ID: |
60314 |
| Uniprot ID: |
MYG1_HUMAN |
| Immunogen Region: |
48-376 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 48-376 of human C12orf10 (NP_067653.3). |
| Immunogen Sequence: |
GTHNGTFHCDEALACALLRL LPEYRDAEIVRTRDPEKLAS CDIVVDVGGEYDPRRHRYDH HQRSFTETMSSLSPGKPWQT KLSSAGLIYLHFGHKLLAQL LGTSEEDSMVGTLYDKMYEN FVEEVDAVDNGISQWAEGEP RYALTTTLSARVARLNPTWN HPDQDTEAGFKRAMDLVQEE FLQRLDFYQHSWLPARALVE EALAQRFQVDPSGEIVELAK GACPWKEHLYHLESGLSPP |
| Tissue Specificity | Ubiquitously expressed, with highest levels in testis. |
| Function | 3'-5' RNA exonuclease which cleaves in situ on specific transcripts in both nucleus and mitochondrion. Involved in regulating spatially segregated organellar RNA processing, acts as a coordinator of nucleo-mitochondrial crosstalk. In nucleolus, processes pre-ribosomal RNA involved in ribosome assembly and alters cytoplasmic translation. In mitochondrial matrix, processes 3'-termini of the mito-ribosomal and messenger RNAs and controls translation of mitochondrial proteins (Probable). |
| Protein Name | Myg1 Exonuclease |
| Cellular Localisation | NucleusNucleoplasmMitochondrion MatrixNucleolus |
| Alternative Antibody Names | Anti-Myg1 Exonuclease antibodyAnti-MYG1 antibodyAnti-C12orf10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
