| Tissue Specificity | Ubiquitously expressed. |
| Function | Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation. Plays a role in the glycosylation of BMPR1A and regulation of its protein stability. Essential for extraembryonic development during early embryogenesis. |
| Protein Name | Beta-1 -4-Galactosyltransferase 5Beta-1 -4-Galtase 5Beta4gal-T5B4gal-T5Beta-1 -4-Galt IiGlucosylceramide Beta-1 -4-GalactosyltransferaseLactosylceramide SynthaseLaccer SynthaseUdp-Gal -Beta-Glcnac Beta-1 -4-Galactosyltransferase 5Udp-Galactose -Beta-N-Acetylglucosamine Beta-1 -4-Galactosyltransferase 5 |
| Database Links | Reactome: R-HSA-2022854Reactome: R-HSA-913709Reactome: R-HSA-975577Reactome: R-HSA-9840309 |
| Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinTrans Cisternae Of Golgi Stack |
| Alternative Antibody Names | Anti-Beta-1 -4-Galactosyltransferase 5 antibodyAnti-Beta-1 -4-Galtase 5 antibodyAnti-Beta4gal-T5 antibodyAnti-B4gal-T5 antibodyAnti-Beta-1 -4-Galt Ii antibodyAnti-Glucosylceramide Beta-1 -4-Galactosyltransferase antibodyAnti-Lactosylceramide Synthase antibodyAnti-Laccer Synthase antibodyAnti-Udp-Gal -Beta-Glcnac Beta-1 -4-Galactosyltransferase 5 antibodyAnti-Udp-Galactose -Beta-N-Acetylglucosamine Beta-1 -4-Galactosyltransferase 5 antibodyAnti-B4GALT5 antibody |
Information sourced from Uniprot.org
