| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-B4GALT5 (60-160) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
B4GALT5 |
| Gene ID: |
9334 |
| Uniprot ID: |
B4GT5_HUMAN |
| Immunogen Region: |
60-160 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 60-160 of human B4GALT5 (NP_004767.1). |
| Immunogen Sequence: |
IGAQVYEQVLRSAYAKRNSS VNDSDYPLDLNHSETFLQTT TFLPEDFTYFANHTCPERLP SMKGPIDINMSEIGMDYIHE LFSKDPTIKLGGHWKPSDCM P |
| Tissue Specificity | Ubiquitously expressed. |
| Function | Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation. Plays a role in the glycosylation of BMPR1A and regulation of its protein stability. Essential for extraembryonic development during early embryogenesis. |
| Protein Name | Beta-1 -4-Galactosyltransferase 5Beta-1 -4-Galtase 5Beta4gal-T5B4gal-T5Beta-1 -4-Galt IiGlucosylceramide Beta-1 -4-GalactosyltransferaseLactosylceramide SynthaseLaccer SynthaseUdp-Gal -Beta-Glcnac Beta-1 -4-Galactosyltransferase 5Udp-Galactose -Beta-N-Acetylglucosamine Beta-1 -4-Galactosyltransferase 5 |
| Database Links | Reactome: R-HSA-2022854Reactome: R-HSA-913709Reactome: R-HSA-975577 |
| Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinTrans Cisternae Of Golgi Stack |
| Alternative Antibody Names | Anti-Beta-1 -4-Galactosyltransferase 5 antibodyAnti-Beta-1 -4-Galtase 5 antibodyAnti-Beta4gal-T5 antibodyAnti-B4gal-T5 antibodyAnti-Beta-1 -4-Galt Ii antibodyAnti-Glucosylceramide Beta-1 -4-Galactosyltransferase antibodyAnti-Lactosylceramide Synthase antibodyAnti-Laccer Synthase antibodyAnti-Udp-Gal -Beta-Glcnac Beta-1 -4-Galactosyltransferase 5 antibodyAnti-Udp-Galactose -Beta-N-Acetylglucosamine Beta-1 -4-Galactosyltransferase 5 antibodyAnti-B4GALT5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
