| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ATP6V1C1 (300-382) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ATP6V1C1 |
| Gene ID: |
528 |
| Uniprot ID: |
VATC1_HUMAN |
| Immunogen Region: |
300-382 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 300-382 of human ATP6V1C1 (NP_001686.1). |
| Immunogen Sequence: |
LRVFVESVLRYGLPVNFQAM LLQPNKKTLKKLREVLHELY KHLDSSAAAIIDAPMDIPGL NLSQQEYYPYVYYKIDCNLL EFK |
| Tissue Specificity | Ubiquitous. |
| Function | Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. |
| Protein Name | V-Type Proton Atpase Subunit C 1V-Atpase Subunit C 1Vacuolar Proton Pump Subunit C 1 |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-77387Reactome: R-HSA-917977Reactome: R-HSA-9639288Reactome: R-HSA-983712 |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembranePeripheral Membrane ProteinClathrin-Coated Vesicle Membrane |
| Alternative Antibody Names | Anti-V-Type Proton Atpase Subunit C 1 antibodyAnti-V-Atpase Subunit C 1 antibodyAnti-Vacuolar Proton Pump Subunit C 1 antibodyAnti-ATP6V1C1 antibodyAnti-ATP6C antibodyAnti-ATP6D antibodyAnti-VATC antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
