| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ATCAY (1-105) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ATCAY |
| Gene ID: |
85300 |
| Uniprot ID: |
ATCAY_HUMAN |
| Immunogen Region: |
1-105 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-105 of human ATCAY (NP_149053.1). |
| Immunogen Sequence: |
MGTTEATLRMENVDVKEEWQ DEDLPRPLPEETGVELLGSP VEDTSSPPNTLNFNGAHRKR KTLVAPEINISLDQSEGSLL SDDFLDTPDDLDINVDDIET PDETD |
| Post Translational Modifications | Cleaved by CASP3 and CASP7. The potential C-terminal product released by CASP3 cleavage may inhibit the ERK signaling pathway through MAP2K2. May be ubiquitinated by STUB1. |
| Function | Functions in the development of neural tissues, particularly the postnatal maturation of the cerebellar cortex. May play a role in neurotransmission through regulation of glutaminase/GLS, an enzyme responsible for the production in neurons of the glutamate neurotransmitter. Alternatively, may regulate the localization of mitochondria within axons and dendrites. |
| Protein Name | CaytaxinAtaxia Cayman Type ProteinBnip-2-HomologyBnip-H |
| Cellular Localisation | Cell ProjectionAxonDendritePresynapseMitochondrionGrowth ConeCytoplasm |
| Alternative Antibody Names | Anti-Caytaxin antibodyAnti-Ataxia Cayman Type Protein antibodyAnti-Bnip-2-Homology antibodyAnti-Bnip-H antibodyAnti-ATCAY antibodyAnti-KIAA1872 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
