| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ASIC5 |
| Gene ID: | 51802 |
| Uniprot ID: | ASIC5_HUMAN |
| Immunogen Region: | 140-330 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 140-330 of human ASIC5 (NP_059115.1). |
| Immunogen Sequence: | HLQEITANSTGSREATDFAA SHQNFSIVEFIRNKGFYLNN STLLDCEFFGKPCSPKDFAH VFTEYGNCFTFNHGETLQAK RKVSVSGRGLSLLFNVNQEA FTDNPALGFVDAGIIFVIHS PKKVPQFDGLGLLSPVGMHA RVTIRQVKTVHQEYPWGECN PNIKLQNFSSYSTSGCLKEC KAQHIKKQCGC |
| Tissue Specificity | Detected in small intestine, duodenum and jejunum. Detected at very low levels in testis and rectum. |
| Function | Cation channel that gives rise to very low constitutive currents in the absence of activation. The activated channel exhibits selectivity for sodium, and is inhibited by amiloride. |
| Protein Name | Acid-Sensing Ion Channel 5Asic5Amiloride-Sensitive Cation Channel 5Human Intestine Na(+ ChannelHinac |
| Database Links | Reactome: R-HSA-2672351 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Acid-Sensing Ion Channel 5 antibodyAnti-Asic5 antibodyAnti-Amiloride-Sensitive Cation Channel 5 antibodyAnti-Human Intestine Na(+ Channel antibodyAnti-Hinac antibodyAnti-ASIC5 antibodyAnti-ACCN5 antibodyAnti-HINAC antibody |
Information sourced from Uniprot.org