| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ARSE (520-589) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ARSL |
| Gene ID: |
415 |
| Uniprot ID: |
ARSL_HUMAN |
| Immunogen Region: |
520-589 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 520-589 of human ARSE (NP_000038.2). |
| Immunogen Sequence: |
PSETHILTPASEPVFYQVME RVQQAVWEHQRTLSPVPLQL DRLGNIWRPWLQPCCGPFPL CWCLREDDPQ |
| Tissue Specificity | Expressed in the pancreas, liver and kidney. |
| Post Translational Modifications | N-glycosylated. The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. |
| Function | Exhibits arylsulfatase activity towards the artificial substrate 4-methylumbelliferyl sulfate. May be essential for the correct composition of cartilage and bone matrix during development. Has no activity toward steroid sulfates. |
| Protein Name | Arylsulfatase LArylsulfatase EAse |
| Database Links | Reactome: R-HSA-1660662Reactome: R-HSA-1663150 |
| Cellular Localisation | Golgi ApparatusGolgi Stack |
| Alternative Antibody Names | Anti-Arylsulfatase L antibodyAnti-Arylsulfatase E antibodyAnti-Ase antibodyAnti-ARSL antibodyAnti-ARSE antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
