Anti-ARMCX3 antibody (40-140) (STJ111803)

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STJ111803
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:200-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ARMCX3
Gene ID: 51566
Uniprot ID: ARMX3_HUMAN
Immunogen Region: 40-140
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 40-140 of human ARMCX3 (NP_057691.1).
Immunogen Sequence: EGGSGDVDDAGDCSGARYND WSDDDDDSNESKSIVWYPPW ARIGTEAGTRARARARARAT RARRAVQKRASPNSDDTVLS PQELQKVLCLVEMSEKPYIL E
Function Regulates mitochondrial aggregation and transport in axons in living neurons. May link mitochondria to the TRAK2-kinesin motor complex via its interaction with Miro and TRAK2. Mitochondrial distribution and dynamics is regulated through ARMCX3 protein degradation, which is promoted by PCK and negatively regulated by WNT1. Enhances the SOX10-mediated transactivation of the neuronal acetylcholine receptor subunit alpha-3 and beta-4 subunit gene promoters.
Protein Name Armadillo Repeat-Containing X-Linked Protein 3
Arm Protein Lost In Epithelial Cancers On Chromosome X 3
Protein Alex3
Database Links Reactome: R-HSA-9013404
Cellular Localisation Mitochondrion Outer Membrane
Single-Pass Membrane Protein
Cytoplasm
Nucleus
Alternative Antibody Names Anti-Armadillo Repeat-Containing X-Linked Protein 3 antibody
Anti-Arm Protein Lost In Epithelial Cancers On Chromosome X 3 antibody
Anti-Protein Alex3 antibody
Anti-ARMCX3 antibody
Anti-ALEX3 antibody
Anti-BM-017 antibody
Anti-UNQ2517 antibody
Anti-PRO6007 antibody

Information sourced from Uniprot.org

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