| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ARMCX3 (40-140) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ARMCX3 |
| Gene ID: |
51566 |
| Uniprot ID: |
ARMX3_HUMAN |
| Immunogen Region: |
40-140 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 40-140 of human ARMCX3 (NP_057691.1). |
| Immunogen Sequence: |
EGGSGDVDDAGDCSGARYND WSDDDDDSNESKSIVWYPPW ARIGTEAGTRARARARARAT RARRAVQKRASPNSDDTVLS PQELQKVLCLVEMSEKPYIL E |
| Function | Regulates mitochondrial aggregation and transport in axons in living neurons. May link mitochondria to the TRAK2-kinesin motor complex via its interaction with Miro and TRAK2. Mitochondrial distribution and dynamics is regulated through ARMCX3 protein degradation, which is promoted by PCK and negatively regulated by WNT1. Enhances the SOX10-mediated transactivation of the neuronal acetylcholine receptor subunit alpha-3 and beta-4 subunit gene promoters. |
| Protein Name | Armadillo Repeat-Containing X-Linked Protein 3Arm Protein Lost In Epithelial Cancers On Chromosome X 3Protein Alex3 |
| Database Links | Reactome: R-HSA-9013404 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Membrane ProteinCytoplasmNucleus |
| Alternative Antibody Names | Anti-Armadillo Repeat-Containing X-Linked Protein 3 antibodyAnti-Arm Protein Lost In Epithelial Cancers On Chromosome X 3 antibodyAnti-Protein Alex3 antibodyAnti-ARMCX3 antibodyAnti-ALEX3 antibodyAnti-BM-017 antibodyAnti-UNQ2517 antibodyAnti-PRO6007 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
