| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ARAP2 (1405-1704) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ARAP2 |
| Gene ID: |
116984 |
| Uniprot ID: |
ARAP2_HUMAN |
| Immunogen Region: |
1405-1704 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1405-1704 of human ARAP2 (NP_056045.2). |
| Immunogen Sequence: |
LAEPGSAYLVVKRFLTADTI KHCSDRSTLGSIKEGILKIK EEPSKILSGNKFQDRYFVLR DGFLFLYKDVKSSKHDKMFS LSSMKFYRGVKKKMKPPTSW GLTAYSEKHHWHLCCDSSRT QTEWMTSIFIAQHEYDIWPP AGKERKRSITKNPKIGGLPL IPIQHEGNATLARKNIESAR AELERLRLSEKCDKESVDSS LKERASMVAHCLEHKDDKLR NRPRKHRSFNCLEDTEPEA |
| Tissue Specificity | Detected in brain, thymus, lymph node, thyroid, spinal cord, trachea, heart, skeletal muscle, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes. |
| Function | Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. |
| Protein Name | Arf-Gap With Rho-Gap Domain - Ank Repeat And Ph Domain-Containing Protein 2Centaurin-Delta-1Cnt-D1Protein Parx |
| Database Links | Reactome: R-HSA-8980692Reactome: R-HSA-9013148Reactome: R-HSA-9013149Reactome: R-HSA-9013423 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Arf-Gap With Rho-Gap Domain - Ank Repeat And Ph Domain-Containing Protein 2 antibodyAnti-Centaurin-Delta-1 antibodyAnti-Cnt-D1 antibodyAnti-Protein Parx antibodyAnti-ARAP2 antibodyAnti-CENTD1 antibodyAnti-KIAA0580 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
