| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-AOAH (306-575) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AOAH |
| Gene ID: |
313 |
| Uniprot ID: |
AOAH_HUMAN |
| Immunogen Region: |
306-575 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 306-575 of human AOAH (NP_001628.1). |
| Immunogen Sequence: |
GFLDSTVGIKEKSIYLRLWK RNHCNHRDYQNISRNGASSR NLKKFIESLSRNKVLDYPAI VIYAMIGNDVCSGKSDPVPA MTTPEKLYSNVMQTLKHLNS HLPNGSHVILYGLPDGTFLW DNLHNRYHPLGQLNKDMTYA QLYSFLNCLQVSPCHGWMSS NKTLRTLTSERAEQLSNTLK KIAASEKFTNFNLFYMDFAF HEIIQEWQKRGGQPWQLIEP VDGFHPNEVALLLLADHFW |
| Post Translational Modifications | Cleaved into a large and a small subunit. The small subunit is N-glycosylated. |
| Function | Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides. By breaking down LPS, terminates the host response to bacterial infection and prevents prolonged and damaging inflammatory responses. In peritoneal macrophages, seems to be important for recovery from a state of immune tolerance following infection by Gram-negative bacteria. |
| Protein Name | Acyloxyacyl Hydrolase Cleaved Into - Acyloxyacyl Hydrolase Small Subunit - Acyloxyacyl Hydrolase Large Subunit |
| Cellular Localisation | SecretedCytoplasmic VesicleDetected In Urine |
| Alternative Antibody Names | Anti-Acyloxyacyl Hydrolase Cleaved Into - Acyloxyacyl Hydrolase Small Subunit - Acyloxyacyl Hydrolase Large Subunit antibodyAnti-AOAH antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
