| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ANKRD13A |
| Gene ID: |
88455 |
| Uniprot ID: |
AN13A_HUMAN |
| Immunogen Region: |
1-240 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human ANKRD13A (NP_149112.1). |
| Immunogen Sequence: |
MSSACDAGDHYPLHLLVWKN DYRQLEKELQGQNVEAVDPR GRTLLHLAVSLGHLESARVL LRHKADVTKENRQGWTVLHE AVSTGDPEMVYTVLQHRDYH NTSMALEGVPELLQKILEAP DFYVQMKWEFTSWVPLVSRI CPNDVCRIWKSGAKLRVDIT LLGFENMSWIRGRRSFIFKG EDNWAELMEVNHDDKVVTTE RFDLSQEMERLTLDLMKPKS REVERRLTSPVINTSLDTK |
| Post Translational Modifications | Monoubiquitinated, inhibits interaction with ubiquitinated EGFR. |
| Function | Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane. |
| Protein Name | Ankyrin Repeat Domain-Containing Protein 13aProtein Ke03 |
| Cellular Localisation | Cell MembraneLate EndosomeInteraction With Egfr May Enhance Association With The Cell Membrane |
| Alternative Antibody Names | Anti-Ankyrin Repeat Domain-Containing Protein 13a antibodyAnti-Protein Ke03 antibodyAnti-ANKRD13A antibodyAnti-ANKRD13 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
