| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-AGTPBP1 (320-520) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AGTPBP1 |
| Gene ID: |
23287 |
| Uniprot ID: |
CBPC1_HUMAN |
| Immunogen Region: |
320-520 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 320-520 of human AGTPBP1 (NP_056054.2). |
| Immunogen Sequence: |
PPEVDDVVDESDDNDDIDVE AENETENEDDLDQNFKNDDI ETDINKLKPQQEPGRTIEDL KMYEHLFPELVDDFQDYDLI SKEPKPFVFEGKVRGPIVVP TAGEETSGNSGNLRKVVMKE NISSKGDEGEKKSTFMDLAK EDIKDNDRTLQQQPGDQNRT ISSVHGLNNDIVKALDRITL QNIPSQTAPGFTAEMKKDCS L |
| Function | Metallocarboxypeptidase that mediates protein deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of alpha-tubulin as well as non-tubulin proteins such as MYLK. Involved in KLF4 deglutamylation which promotes KLF4 proteasome-mediated degradation, thereby negatively regulating cell pluripotency maintenance and embryogenesis. |
| Protein Name | Cytosolic Carboxypeptidase 1Atp/Gtp-Binding Protein 1Nervous System Nuclear Protein Induced By Axotomy Protein 1 HomologProtein Deglutamylase Ccp1 |
| Database Links | Reactome: R-HSA-8955332 |
| Cellular Localisation | CytoplasmCytosolNucleusMitochondrionLocalizes In Both The Cytoplasm And Nuclei Of Interphase And Dividing Cells |
| Alternative Antibody Names | Anti-Cytosolic Carboxypeptidase 1 antibodyAnti-Atp/Gtp-Binding Protein 1 antibodyAnti-Nervous System Nuclear Protein Induced By Axotomy Protein 1 Homolog antibodyAnti-Protein Deglutamylase Ccp1 antibodyAnti-AGTPBP1 antibodyAnti-CCP1 antibodyAnti-KIAA1035 antibodyAnti-NNA1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
