| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ADD1 |
| Gene ID: | 118 |
| Uniprot ID: | ADDA_HUMAN |
| Immunogen Region: | 60-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-300 of human ADD1 (NP_054908.2). |
| Immunogen Sequence: | MILQSPAFCEELESMIQEQF KKGKNPTGLLALQQIADFMT TNVPNVYPAAPQGGMAALNM SLGMVTPVNDLRGSDSIAYD KGEKLLRCKLAAFYRLADLF GWSQLIYNHITTRVNSEQEH FLIVPFGLLYSEVTASSLVK INLQGDIVDRGSTNLGVNQA GFTLHSAIYAARPDVKCVVH IHTPAGAAVSAMKCGLLPIS PEALSLGEVAYHDYHGILVD EEEKVLIQKNLGPKSKVLI |
| Tissue Specificity | Expressed in all tissues. Found in much higher levels in reticulocytes than the beta subunit. |
| Function | Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin. |
| Protein Name | Alpha-AdducinErythrocyte Adducin Subunit Alpha |
| Database Links | Reactome: R-HSA-264870Reactome: R-HSA-381038Reactome: R-HSA-5223345 |
| Cellular Localisation | CytoplasmCytoskeletonCell MembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Alpha-Adducin antibodyAnti-Erythrocyte Adducin Subunit Alpha antibodyAnti-ADD1 antibodyAnti-ADDA antibody |
Information sourced from Uniprot.org