| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
COQ8B |
| Gene ID: |
79934 |
| Uniprot ID: |
COQ8B_HUMAN |
| Immunogen Region: |
1-90 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human ADCK4 (NP_079152.3). |
| Immunogen Sequence: |
MWLKVGGLLRGTGGQLGQTV GWPCGALGPGPHRWGPCGGS WAQKFYQDGPGRGLGEEDIR RAREARPRKTPRPQLSDRSR ERKVPASRIS |
| Tissue Specificity | Widely expressed, including renal podocytes. |
| Function | Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is unclear: does not show any protein kinase activity. Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway. Required for podocyte migration. |
| Protein Name | Atypical Kinase Coq8b - MitochondrialAarf Domain-Containing Protein Kinase 4Coenzyme Q Protein 8b |
| Database Links | Reactome: R-HSA-2142789 |
| Cellular Localisation | Mitochondrion MembraneSingle-Pass Membrane ProteinCytoplasmCytosolCell Membrane |
| Alternative Antibody Names | Anti-Atypical Kinase Coq8b - Mitochondrial antibodyAnti-Aarf Domain-Containing Protein Kinase 4 antibodyAnti-Coenzyme Q Protein 8b antibodyAnti-COQ8B antibodyAnti-ADCK4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
