Anti-ACHE antibody (C-Term) (STJ70663)

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STJ70663-100
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Host: Goat
Applications: Pep-ELISA/WB/IF/FC
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Goat polyclonal antibody anti-ACHE (C-Term) is suitable for use in ELISA, Western Blot, Immunofluorescence and Flow Cytometry research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: Peptide ELISA: antibody detection limit dilution 1:32000.
WB: Approx 70kDa band observed in HepG2 and Jurkat cell lysates (calculated MW of 67.8kDa according to NP_000656.1). Recommended concentration: 0.3-1µg/ml. Primary incubation 1 hour at roo
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: ACHE
Gene ID: 43
Uniprot ID: ACES_HUMAN
Immunogen Region: C-Term
Accession Number: NP_000656.1; NP_001269378.1
Specificity: This antibody is expected to recognise isoform NP_000656.1 only (the ubiquitously expressed, hydrophillic form).
Immunogen Sequence: QFDHYSKQDRCSDL
Function Hydrolyzes rapidly the acetylcholine neurotransmitter released into the synaptic cleft allowing to terminate the signal transduction at the neuromuscular junction. Role in neuronal apoptosis.
Protein Name Acetylcholinesterase
Ache
Database Links Reactome: R-HSA-112311
Reactome: R-HSA-1483191
Reactome: R-HSA-422085
Cellular Localisation Synapse
Secreted
Cell Membrane
Peripheral Membrane Protein
Isoform T: Nucleus
Only Observed In Apoptotic Nuclei
Isoform H: Cell Membrane
Lipid-Anchor
Gpi-Anchor
Extracellular Side
Alternative Antibody Names Anti-Acetylcholinesterase antibody
Anti-Ache antibody
Anti-ACHE antibody

Information sourced from Uniprot.org