||WB, IHC-P, IF-P, ELISA
||Human, Mouse, Rat
||FOR RESEARCH USE ONLY (RUO).
||Rabbit polyclonal antibody anti-Atp-Dependent Translocase Abcb1 (Internal) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
||PBS, 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
||The antibody was affinity-purified from rabbit anti-serum by affinity-chromatography.
||IHC 1:100-1:300ELISA 1:40000
||Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
||ABCB1 polyclonal antibody (Atp-Dependent Translocase Abcb1) binds to endogenous Atp-Dependent Translocase Abcb1 at the amino acid region Internal.
||The antiserum was produced against synthesized peptide derived from human P-glycoprotein 1 at amino acid range 534-583
| Function || Translocates drugs and phospholipids across the membrane. Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins. Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. |
| Protein Name || Atp-Dependent Translocase Abcb1Atp-Binding Cassette Sub-Family B Member 1Multidrug Resistance Protein 1P-Glycoprotein 1Phospholipid Transporter Abcb1Cd Antigen Cd243 |
| Database Links || Reactome: R-HSA-2161517Reactome: R-HSA-382556 |
| Cellular Localisation || Cell MembraneMulti-Pass Membrane ProteinApical Cell Membrane |
| Alternative Antibody Names || Anti-Atp-Dependent Translocase Abcb1 antibodyAnti-Atp-Binding Cassette Sub-Family B Member 1 antibodyAnti-Multidrug Resistance Protein 1 antibodyAnti-P-Glycoprotein 1 antibodyAnti-Phospholipid Transporter Abcb1 antibodyAnti-Cd Antigen Cd243 antibodyAnti-ABCB1 antibodyAnti-MDR1 antibodyAnti-PGY1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance