• Immunohistochemistry analysis of Mdr-1 antibody in paraffin-embedded human brain tissue.

Anti-ABCB1 antibody (Internal) (STJ95057)


Current Stock:
Host: Rabbit
Applications: WB, IHC-P, IF-P, ELISA
Reactivity: Human, Mouse, Rat
Short Description: Rabbit polyclonal antibody anti-Atp-Dependent Translocase Abcb1 (Internal) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS, 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit anti-serum by affinity-chromatography.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:40000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ABCB1
Gene ID: 5243
Uniprot ID: MDR1_HUMAN
Immunogen Region: Internal
Specificity: ABCB1 polyclonal antibody (Atp-Dependent Translocase Abcb1) binds to endogenous Atp-Dependent Translocase Abcb1 at the amino acid region Internal.
Immunogen: The antiserum was produced against synthesized peptide derived from human P-glycoprotein 1 at amino acid range 534-583
Function Translocates drugs and phospholipids across the membrane. Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins. Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Protein Name Atp-Dependent Translocase Abcb1
Atp-Binding Cassette Sub-Family B Member 1
Multidrug Resistance Protein 1
P-Glycoprotein 1
Phospholipid Transporter Abcb1
Cd Antigen Cd243
Database Links Reactome: R-HSA-2161517
Reactome: R-HSA-382556
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Apical Cell Membrane
Alternative Antibody Names Anti-Atp-Dependent Translocase Abcb1 antibody
Anti-Atp-Binding Cassette Sub-Family B Member 1 antibody
Anti-Multidrug Resistance Protein 1 antibody
Anti-P-Glycoprotein 1 antibody
Anti-Phospholipid Transporter Abcb1 antibody
Anti-Cd Antigen Cd243 antibody
Anti-ABCB1 antibody
Anti-MDR1 antibody
Anti-PGY1 antibody

Information sourced from Uniprot.org

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