| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-A4GALT (244-353) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
A4GALT |
| Gene ID: |
53947 |
| Uniprot ID: |
A4GAT_HUMAN |
| Immunogen Region: |
244-353 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 244-353 of human A4GALT (NP_059132.1). |
| Immunogen Sequence: |
WIWGHQGPQLLTRVFKKWCS IRSLAESRACRGVTTLPPEA FYPIPWQDWKKYFEDINPEE LPRLLSATYAVHVWNKKSQG TRFEATSRALLAQLHARYCP TTHEAMKMYL |
| Tissue Specificity | Ubiquitous. Highly expressed in kidney, heart, spleen, liver, testis and placenta. |
| Function | Catalyzes the transfer of galactose from UDP-alpha-D-galactose to lactosylceramide/beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide(d18:1(4E)) to produce globotriaosylceramide/globoside Gb3Cer (d18:1(4E)). Also able to transfer galactose to galactosylceramide/beta-D-Gal-(1<->1')-Cer. Globoside Gb3Cer is a glycosphingolipid of the globo serie, one of the major types of neutral root structures of glycosphingolipids, that constitute a significant portion of mammalian cell membranes (Probable). Globotriaosylceramide/globoside Gb3Cer in blood and tissue cell membranes is the antigen Pk of blood histogroup P. (Microbial infection) Globotriaosylceramide is one of the cellular ligands for bacterial verotoxins. |
| Protein Name | Lactosylceramide 4-Alpha-GalactosyltransferaseAlpha-1 -4-N-AcetylglucosaminyltransferaseAlpha-1 -4-GalactosyltransferaseAlpha4gal-T1Cd77 SynthaseGlobotriaosylceramide SynthaseGb3 SynthaseP1/Pk SynthaseUdp-Galactose -Beta-D-Galactosyl-Beta1-R 4-Alpha-D-Galactosyltransferase |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Lactosylceramide 4-Alpha-Galactosyltransferase antibodyAnti-Alpha-1 -4-N-Acetylglucosaminyltransferase antibodyAnti-Alpha-1 -4-Galactosyltransferase antibodyAnti-Alpha4gal-T1 antibodyAnti-Cd77 Synthase antibodyAnti-Globotriaosylceramide Synthase antibodyAnti-Gb3 Synthase antibodyAnti-P1/Pk Synthase antibodyAnti-Udp-Galactose -Beta-D-Galactosyl-Beta1-R 4-Alpha-D-Galactosyltransferase antibodyAnti-A4GALT antibodyAnti-A14GALT antibodyAnti-A4GALT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
