ZDHHC9 Positive Control for STJ503570 peptide (STJ505314)

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STJ505314-5

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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: ZDHHC9 Positive Control for STJ503570 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: ZDHHC9
Gene ID: 51114
Uniprot ID: ZDHC9_HUMAN
Specificity: This is positive control is recommended for use in combination with ZDHHC9 antibody STJ503570.
Tissue Specificity Highly expressed in kidney, skeletal muscle, brain, lung and liver. Absent in thymus, spleen and leukocytes.
Function Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates (Probable). The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS. May have a palmitoyltransferase activity toward the beta-2 adrenergic receptor/ADRB2 and therefore regulate G protein-coupled receptor signaling. (Microbial infection) Through a sequential action with ZDHHC20, rapidly and efficiently palmitoylates SARS coronavirus-2/SARS-CoV-2 spike protein following its synthesis in the endoplasmic reticulum (ER). In the infected cell, promotes spike biogenesis by protecting it from premature ER degradation, increases half-life and controls the lipid organization of its immediate membrane environment. Once the virus has formed, spike palmitoylation controls fusion with the target cell.
Peptide Name Palmitoyltransferase Zdhhc9
Zinc Finger Dhhc Domain-Containing Protein 9
Dhhc-9
Dhhc9
Zinc Finger Protein 379
Zinc Finger Protein 380
Database Links Reactome: R-HSA-9648002
Reactome: R-HSA-9694548
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Golgi Apparatus Membrane
Alternative Peptide Names Palmitoyltransferase Zdhhc9 protein
Zinc Finger Dhhc Domain-Containing Protein 9 protein
Dhhc-9 protein
Dhhc9 protein
Zinc Finger Protein 379 protein
Zinc Finger Protein 380 protein
ZDHHC9 protein
CXorf11 protein
ZDHHC10 protein
ZNF379 protein
ZNF380 protein
CGI-89 protein
UNQ261 protein
PRO298 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance