XTP4 Blocking Peptide peptide (STJ505077)

SKU:
STJ505077-250

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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: XTP4 Blocking Peptide is synthetically produced from the 40-90 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: MIEN1
Gene ID: 84299
Uniprot ID: MIEN1_HUMAN
Immunogen Region: 40-90
Immunogen: Synthetic peptide taken within amino acid region 40-90 on human XTP4 protein.
Tissue Specificity Among normal tissues, present only in Leydig cells. Strongly up-regulated in breast cancers and in brain cancer distant metastasis (at protein level). Up-regulated in prostate cancer cells and in the higher grades of prostate adenocarcinoma (at protein level).
Post Translational Modifications Isoprenylation facilitates association with the plasma membrane and enhances the migratory phenotype of cells by inducing increased filopodia formation.
Function Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process.
Peptide Name Migration And Invasion Enhancer 1
Hbv X-Transactivated Gene 4 Protein
Hbv Xag-Transactivated Protein 4
Protein C35
Cellular Localisation Cytoplasm
Cytosol
Cell Membrane
Lipid-Anchor
Cytoplasmic Side
Concentrates At The Leading Edge Of Migrating Cells
Localizes Outside Membrane Raft Regions
Alternative Peptide Names Migration And Invasion Enhancer 1 protein
Hbv X-Transactivated Gene 4 Protein protein
Hbv Xag-Transactivated Protein 4 protein
Protein C35 protein
MIEN1 protein
C17orf37 protein
RDX12 protein
XTP4 protein

Information sourced from Uniprot.org

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