• Rat VDR (Vitamin D Receptor) Sandwich ELISA Kit (STJE0012997)

Rat VDR (Vitamin D Receptor) Sandwich ELISA Kit (STJE0012997)

SKU:
STJE0012997

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Applications: ELISA
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.247ng/mL
Detection Limit: 0.625-40ng/mL
Short Description: This VDR Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Vdr
Gene ID: 24873
Uniprot ID: VDR_RAT
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Detected in intestine and kidney.
Post Translational Modifications
Function Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells. Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR. The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes. Plays a central role in calcium homeostasis. Also functions as a receptor for the secondary bile acid lithocholic acid (LCA) and its metabolites.
Protein Name Vitamin D3 Receptor
Vdr
1 -25-Dihydroxyvitamin D3 Receptor
Nuclear Receptor Subfamily 1 Group I Member 1
Database Links Reactome: R-RNO-196791
Reactome: -RNO-383280
Reactome: -RNO-4090294
Cellular Localisation Nucleus
Cytoplasm
Localizes Mainly To The Nucleus
Translocated Into The Nucleus Via Both Ligand-Dependent And Ligand-Independent Pathways
Ligand-Independent Nuclear Translocation Is Mediated By Ipo4
Alternative ELISA Names Vitamin D3 Receptor ELISA kit
Vdr ELISA kit
1 -25-Dihydroxyvitamin D3 Receptor ELISA kit
Nuclear Receptor Subfamily 1 Group I Member 1 ELISA kit
Vdr ELISA kit
Nr1i1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance