• Rat SPTAN1 (Alpha-Fodrin) Sandwich ELISA Kit (STJE0012325)

Rat SPTAN1 (Alpha-Fodrin) Sandwich ELISA Kit (STJE0012325)

SKU:
STJE0012325

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Applications: ELISA
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 2.3pg/mL
Detection Limit: 7.81-500pg/mL
Short Description: This SPTAN1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Sptan1
Gene ID: 64159
Uniprot ID: SPTN1_RAT
Sample Type: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity Expressed in the foot process layer of podocytes in the kidney glomerulus and in tubules (at protein level).
Post Translational Modifications Phosphorylation of Tyr-1176 decreases sensitivity to cleavage by calpain in vitro.
Function Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
Protein Name Spectrin Alpha Chain - Non-Erythrocytic 1
Alpha-Ii Spectrin
Fodrin Alpha Chain
Database Links Reactome: R-RNO-264870
Reactome: -RNO-375165
Reactome: -RNO-445095
Reactome: -RNO-5673001
Reactome: -RNO-6798695
Reactome: -RNO-6807878
Reactome: -RNO-9013420
Reactome: -RNO-9013424
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Cortex
Expressed Along The Cell Membrane In Podocytes And Presumptive Tubule Cells During Glomerulogenesis And Is Expressed Along Lateral Cell Margins In Tubule Cells
Alternative ELISA Names Spectrin Alpha Chain - Non-Erythrocytic 1 ELISA kit
Alpha-Ii Spectrin ELISA kit
Fodrin Alpha Chain ELISA kit
Sptan1 ELISA kit
Spna2 ELISA kit
Spta2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance