| Applications: |
ELISA |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.068ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This PTGES Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Ptges |
| Gene ID: |
59103 |
| Uniprot ID: |
PTGES_RAT |
| Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Terminal enzyme of the cyclooxygenase (COX)-2-mediated prostaglandin E2 (PGE2) biosynthetic pathway. Catalyzes the glutathione-dependent oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) in response to inflammatory stimuli. Plays a key role in inflammation response, fever and pain. Catalyzes also the oxidoreduction of endocannabinoids into prostaglandin glycerol esters and PGG2 into 15-hydroperoxy-PGE2. In addition, displays low glutathione transferase and glutathione-dependent peroxidase activities, toward 1-chloro-2,4-dinitrobenzene and 5-hydroperoxyicosatetraenoic acid (5-HPETE), respectively. |
| Protein Name | Prostaglandin E SynthaseMpges-1Glutathione Peroxidase PtgesGlutathione Transferase PtgesInducible Prostaglandin E SynthaseMicrosomal Prostaglandin E Synthase 1 |
| Database Links | Reactome: R-RNO-2162123 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinCytoplasmPerinuclear RegionColocalizes With Ptgs1/Cox-1 And Ptgs2/Cox-2 In The Perinuclear Compartment |
| Alternative ELISA Names | Prostaglandin E Synthase ELISA kitMpges-1 ELISA kitGlutathione Peroxidase Ptges ELISA kitGlutathione Transferase Ptges ELISA kitInducible Prostaglandin E Synthase ELISA kitMicrosomal Prostaglandin E Synthase 1 ELISA kitPtges ELISA kitPges ELISA kitPig12 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
