| Applications: |
ELISA |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.063ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This NUCB1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
3 hrs |
| Gene Symbol: |
Nucb1 |
| Gene ID: |
84595 |
| Uniprot ID: |
NUCB1_RAT |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Minor constituent of the mineralized matrix of bone. Detected in calvaria, rib cartilage, liver, kidney, spleen, brain, lung, skeletal and heart muscle with highest expression in calvaria and approximately half the amount in kidney, liver and brain. |
| Post Translational Modifications | |
| Function | Major calcium-binding protein of the Golgi which may have a role in calcium homeostasis. Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates alpha subunits of guanine nucleotide-binding proteins (G proteins). |
| Protein Name | Nucleobindin-1Bone 63 Kda Calcium-Binding ProteinCalnuc |
| Database Links | Reactome: R-RNO-381426Reactome: -RNO-8957275 |
| Cellular Localisation | Golgi ApparatusCis-Golgi Network MembranePeripheral Membrane ProteinLumenal SideCytoplasmSecretedA Small Fraction Of The Protein May Be CytoplasmicIn Bone At Least Part Of It Is Found In The Extracellular Matrix And In The Culture Medium Of Calvaria Explants |
| Alternative ELISA Names | Nucleobindin-1 ELISA kitBone 63 Kda Calcium-Binding Protein ELISA kitCalnuc ELISA kitNucb1 ELISA kitNuc ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
